Pleural mesothelioma spreads within the chest cavity, sometimes involving the lung. Metastases can occur in any organ, including the brain, and the onset is typically very slow with the most common presenting symptom being persistent pain localized in the chest. Sometimes the pain is accompanied by severe difficulty breathing, coughing, weight loss and fever.
Peritoneal mesothelioma involves the abdominal cavity and infiltrates the liver, spleen or bowel. As with pleural mesothelioma, pain is the most common complaint. In addition, patients may also experience nausea, vomiting, swelling of the feet, fever, difficulty in moving their bowels and fluid accumulation in the abdominal cavity resulting in an enlarged abdomen.
Cystic mesothelioma is a rare form of benign mesothelioma involving a thin membrane of mesothelial cells that envelopes many of the organs in the abdomen. This type has been diagnosed primarily in young women, and most patients must undergo surgery.
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